Are you wondering about the side effects of Rimadyl? Are you thinking Rimadyl killed my dog? Despite being given by your veterinarian for a medical reason you should be aware of what is Rimadyl and how does it work? Is it safe for dogs to eat it? And Rimadyl side effects in dogs.

It’s high time to learn everything you can about this drug so you can make an informed decision and spot potential problems early.


Pfizer, the world’s largest research-based pharmaceutical firm, manufactures Rimadyl, also known as Carprofen. In 1997, it was initially presented. It’s an NSAID (non-steroidal anti-inflammatory medicine), which is commonly abbreviated as NSAID. The goal of nonsteroidal anti-inflammatory drugs (NSAIDs) is to relieve pain and inflammation. Redness, warmth, swelling, and discomfort are all symptoms of inflammation. NSAIDs work by inhibiting the formation of prostaglandins, which are the molecules that cause inflammation.


If your veterinarian ordered this medication, your dog is most likely suffering from osteoarthritis or has just undergone soft tissue or orthopedic surgery.

Rimadyl is available in caplets or delectable chewable that your dog will undoubtedly devour. Keep the bottle in a secure location where your dog will not be able to reach it. There are three different strengths available: 25 mg, 75 mg, and 100 mg. The amount and frequency of administration are determined by the weight and medical condition of the dog. The effect is usually visible within 1 to 3 hours.


About 15 million dogs with pain, degenerative joint disease, or osteoarthritis are thought to have taken such a prescription. Although NSAID treatments are effective at relieving pain and inflammation, around 3,200 dogs have died as a result of taking them, and nearly 19,000 dogs have had adverse responses to them.

Rimadyl got nearly 13,000 adverse effect reports from the FDA between November 2004 and November 2005, far more than any other dog pain medication. According to Cactus Canyon, the FDA required that Pfizer emphasize “death” in its television advertising and other media after many complaints of dogs dying, and Pfizer chose to stop showing these ads entirely.


So, what’s the issue with this medication? Rimadyl and other nonsteroidal anti-inflammatory drugs (NSAIDs) act by preventing the synthesis of “prostaglandins,” which are known to cause inflammation in injured or aging joints. According to the Senior Dog Project, prostaglandins are required for several other bodily functions, and when production is halted, the digestive system, liver, and kidneys are all affected.


  • Never combine corticosteroids or aspirin with an NSAID. According to Novartis’ David Stansfield, this could result in substantial side effects.
  • Before taking NSAIDs, have your dog undergo a comprehensive physical examination.
  • Request bloodwork from your veterinarian to examine your dog’s liver and kidneys before, during, and after using NSAIDs. This will allow you to detect a reaction before it causes irreversible damage. The sooner issues are identified, the higher the prospects of healing.
  • Labrador retrievers given carprofen for more than three weeks appear to be more susceptible to liver problems; nevertheless, Labradors are prone to joint problems, and any dog breed, Labrador or not, can be impacted.
  • Consider that older canines accounted for almost 70% of all possible adverse medication event reports received by Pfizer. Keep in mind, however, that severe effects have been reported in dogs as young as 15 months old!
  • If you are also giving other drugs or homeopathic treatments, such as turmeric, see your veterinarian because these may interact with NSAIDs.
  • In some circumstances, veterinarians recommend Tramadol in addition to Rimadyl, resulting in a reduction in Rimadyl dosage. Nutraceuticals may be an alternative to Rimadyl that can be used in conjunction with it to reduce the dosage.
  • Rimadyl interferes with proper blood coagulation, thus any bleeding concerns should be reported to your veterinarian. As a result, Rimadyl should be stopped a few days before surgery.
  • Jaundice is a yellowing of the gums, skin, or whites of the eyes that might signal liver disorders. NSAIDs have the potential to reduce blood flow to the liver, limiting its ability to eliminate toxins from the body. If the medicine isn’t stopped within a certain amount of time, irreparable liver damage can occur.
  • Changes in behavior, such as a decreased or increased level of activity, and uncoordinated stride, seizures, or hostility, should be reported.
  • Itching, scabs, face swelling, hives, and redness on the skin imply an allergy to the substance.
  • Rimadyl’s safety in pregnant or nursing dogs has yet to be determined.
  • Any negative effects or odd changes in your dog should be reported right away. The following are a few of the most prevalent.
  • Look for signs of gastrointestinal distress in your dogs, such as lack of appetite, vomiting, or diarrhea. Giving Rimadyl with food may reduce the likelihood of stomach problems, although some dogs still have them.
  • Rimadyl thins the mucous lining of the stomach, which can lead to ulcers. Blood in the stool (typically in the form of dark, tarry stools) or flecks of blood in the vomit are signs of ulcers. Internal bleeding and shock can occur when ulcers bleed extensively. Gums that are white and pale could indicate a life-threatening problem.
  • Kidney issues might be detected by changes in drinking or urine patterns.


It’s understandable if dog owners are nervous when Rimadyl or other NSAIDs are prescribed for their pets. Other NSAIDs, such as Deramaxx, Metacam, and Etodolac, have the potential for side effects as well.

So, what natural alternatives are there? There are several, but they may not work as quickly or as effectively as a prescription anti-inflammatory treatment, which is one of the reasons they aren’t as popular. In addition, they are unlikely to help with acute injuries like a torn cruciate ligament. Rather, they appear to be more effective in the treatment of persistent arthritis.


This is a completely risk-free supplement. Glucosamine is derived mostly from the shells of crustaceans, whereas chondroitin can be derived from cow cartilage, as well as shark and whale cartilage. This supplement is designed to help the cartilage mend and minimize discomfort. Fortunately, the risk of negative effects is extremely minimal. The possibilities of serious side effects, according to Drs. Foster and Smith, who have sold tens of thousands of doses of this supplement, are exceedingly low, and they have yet to see one. Some dogs may experience vomiting and diarrhea, although this is rare, and these symptoms usually go away when the supplement is given with food.


Rimadyl appears to be and will continue to be a contentious medicine. Some compare it to the human pain reliever Vioxx, only Rimadyl is still on the market, is aggressively marketed, and is one of the most commonly prescribed canine drugs. While many dogs improve dramatically when given this medicine (such as those who can’t move or sleep without it), it appears that some have negative effects and, in some circumstances, die.

Rimadyl isn’t the only medicine that has been linked to side effects. Previcox, Derammax, Zubrin, and Metacam have also been linked to side effects, though not as many as Rimadyl because they’re not as commonly prescribed.


The final line is that Rimadyl does pose some hazards. Owners should be made aware of them, and a Client Information Sheet should always be provided. If your veterinarian determines that the drug’s advantages outweigh the risks, you must be aware of these dangers. When it comes to your pet’s health, knowledge is the ultimate power, allowing you to make the best, most educated decisions possible.

You might also like…

Spread the love